Synlett · 2017 · 28 citations · 0 references
Natural SciencesChemistryCatalysisOrganic ChemistryCatalyst DesignCatalytic MaterialsCatalytic MechanismsAlkane FunctionalizationCatalytic Reaction MechanismsHeterocycle FunctionalizationMetal CatalystsMild Reaction ConditionsTransition Metal CatalystsTransition Metal-catalyzed SynthesisTransition-metal-catalyzed Functionalization
Autoxidative <i>sp<sup>3</sup> </i> C–H transformation of diarylmethanes has been demonstrated using O<sub>2</sub>-mediation by <i>t</i>-BuONa. This protocol enables an alternative route for the access to diaryl ketones from benzyl derivatives in good to excellent yields under mild reaction conditions, without transition metal catalysts or additional chemical oxidants.