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Determinants of the increase in ketone concentration during <scp>SGLT2</scp> inhibition in <scp>NGT</scp> , <scp>IFG</scp> and <scp>T2DM</scp> patients

Hussein Al Jobori, Giuseppe Daniele, John M. Adams, Eugênio Cersósimo, Curtis Triplitt, Ralph A. DeFronzo, Muhammad Abdul‐Ghani

Diabetes Obesity and Metabolism · 2017 · 73 citations · 12 references

DOIFull text

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Abstract

Results of the present study demonstrate that SGLT2 inhibition exerts different metabolic effects in non-diabetic individuals as compared to diabetic patients.

References

12

Metabolic response to sodium-glucose cotransporter 2 inhibition in type 2 diabetic patients

Ele Ferrannini, Elza Muscelli, Silvia Frascerra et al. · Journal of Clinical Investigation · 2014 · 1.1K citations · Full text

Euglycemic Diabetic Ketoacidosis: A Potential Complication of Treatment With Sodium–Glucose Cotransporter 2 Inhibition

Anne L. Peters, Elizabeth Buschur, John B. Buse et al. · Diabetes Care · 2015 · 808 citations · Full text

Glucose and free fatty acid metabolism in non-insulin-dependent diabetes mellitus. Evidence for multiple sites of insulin resistance.

Riccardo C. Bonadonna, Stefano DelPrato, Klaus Ratheiser et al. · Journal of Clinical Investigation · 1989 · 803 citations · Full text

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Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production

Aurora Merovci, Carolina Solis‐Herrera, Giuseppe Daniele et al. · Journal of Clinical Investigation · 2014 · 769 citations · Full text

, , +15

Shift to Fatty Substrate Utilization in Response to Sodium–Glucose Cotransporter 2 Inhibition in Subjects Without Diabetes and Patients With Type 2 Diabetes

Ele Ferrannini, Simona Baldi, Silvia Frascerra et al. · Diabetes · 2016 · 691 citations