Complex Roles of Annexin A2 in Host Blood–Brain Barrier Invasion by <i>Cryptococcus neoformans</i>

Abstract

Our work indicated that AnxA2 played complex roles in traversal of C. neoformans across host BMECs, which might be dependent on downstream cofilin to inhibit fungal adhesion but rely on its partner S100A10 to promote cryptococcal transcytosis.