Synthesis and Chemometrics of Thymol and Carvacrol Derivatives as Larvicides against <i>Aedes aegypti</i>.

Abstract

Thymol derivatives were, to a certain extent, more efficient larvicides against <i>Ae. aegypti</i> than carvacrol derivatives, particularly to Rockefeller larvae. The chemometrics tools applied in this study showed that the independent variables indicate a mixed profile. Nevertheless, hydrophobic interactions increased the larvicidal activity.