Current Urology · 2017 · 33 citations · 12 references
MedicineOncologyUrologyGenitourinary OncologyProstate DiseaseUrologic OncologyProstate CancerUrologic Cancer DiagnosisMale Lower Urinary Tract SymptomsMedian AgeProstate Cancer Diagnosis
Prostate cancer is the most common non-cutaneous malignancy in men. It is generally considered a cancer of the elderly, and the median age of presentation is 68 years. However 10% of new diagnoses in the USA occur in men aged ≤ 55 years. This may be due to more prevalent screening nowadays, and may also reflect the diagnosis of an increasingly recognized but underappreciated entity, i.e. early-onset prostate cancer. Patients with early onset prostate cancer pose unique challenges. Current data suggest that early-onset prostate cancer is a distinct phenotype-from both an etiological and clinical perspective- that deserves further attention. We present a case of a 28-year-old man who presented with lower urinary tract symptoms and was diagnosed with advanced stage prostate cancer.
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Patient Age as a Prognostic Factor in Prostate Cancer
Henrik Grönberg, Jan‐Erik Damber, Håkan Jönsson et al. · The Journal of Urology · 1994 · 110 citations
Early onset prostate cancer has a significant genetic component
Ethan M. Lange, Claudia A. Salinas, Kimberly A. Zuhlke et al. · The Prostate · 2011 · 79 citations · Full text
Life Sciences, Genetics, Oncology +10