Concepedia

Publication | Open Access

An endoplasmic reticulum protein, Nogo‐B, facilitates alcoholic liver disease through regulation of kupffer cell polarization

DOIFull Paper Access

85

Citations

30

References

2017

Year

Jin‐Kyu Park, Mingjie Shao, Moon Young Kim, Soon Koo Baik, Mee-Yon Cho, Teruo Utsumi, Ayano Satoh, Xinsho Ouyang, Chuhan Chung, Yasuko Iwakiri
Hepatology

Abstract

Nogo-B is permissive of M1 polarization of Kupffer cells, thereby accentuating liver injury in ALD in humans and mice. Nogo-B in Kupffer cells may represent a new therapeutic target for ALD. (Hepatology 2017;65:1720-1734).

References

YearCitations

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