Concepedia

Publication | Open Access

Multifunctional Mitochondrial Epac1 Controls Myocardial Cell Death

DOIFull Paper Access

101

Citations

32

References

2017

Year

Loubina Fazal, Marion Laudette, Sílvia Paula-Gomes, Sandrine Pons, Caroline Conte, Florence Tortosa, Pierre Sicard, Yannis Sainte–Marie, Malik Bisserier, Olivier Lairez,
Circulation Research

Abstract

Our results reveal the existence, within mitochondria, of different cAMP-Epac1 microdomains that control myocardial cell death. In addition, our findings suggest Epac1 as a promising target for the treatment of ischemia-induced myocardial damage.

References

YearCitations

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