MicroRNA Expression Shows Inflammatory Dysregulation and Tumor‐Like Proliferative Responses in Joints of Patients With Postinfectious Lyme Arthritis

Abstract

During active infection, miRNA expression in SF reflected an immune response associated with bacterial killing, while in postinfectious LA, miRNA expression in SF and synovial tissue reflected chronic inflammation, synovial proliferation, and breakdown of wound repair processes, showing that the nature of the arthritis was altered after spirochetal killing.