Ruthenium(II)‐Catalyzed <i>meta</i> C−H Mono‐ and Difluoromethylations by Phosphine/Carboxylate Cooperation

Abstract

Ruthenium(II)-catalyzed meta-selective C-H (di)fluoromethylation was accomplished by phosphine and carboxylate cooperation. The remote C-H functionalization was characterized by ample substrate scope, thereby setting the stage for meta-(di)fluoromethylation through facile C-H cleavage.