Maturation of cellular Fe-S proteins: an essential function of mitochondria

Abstract

or-ganelles of eukaryotic cells. In additionto their primary function in the cellularenergy supply, they fulfill a variety ofmetabolic tasks such as the urea cycleand the biosynthesis of heme, other co-factors and amino acids. Recent investi-gations have added to this list a newbiosynthetic function of mitochondria,namely the maturation of cellular Fe–Sproteins