PubMed · 1981 · 32 citations · 2 references
Life SciencesBotanyPlant SciencesPlant BiochemistryPlant PhysiologyReproductive ToxicologyPlant Residue EffectsToxic PlantsMass Spectral Data AnalysisMass Spectral FragmentationMass Spectral IdentificationPharmaceutical TeratogenicityTeratogenic Effects Of DrugsToxicity Of Alkaloid-containing PlantsToxicology Of Medicinal PlantsWoody Stems
Nicotiana glauca consumption by pregnant cows or sows produced arthrogryposis and other congenital deformities in their offspring. The plant material administered contained 0.11% anabasine, the suspect teratogen. But concentration varied among various plant parts; woody material was very low but leaves and bark were high. The anabasine was identified by mass spectral fragmentation analysis.
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