Selective Cascade Reaction of Bisallenes via Palladium‐Catalyzed Aerobic Oxidative Carbocyclization–Borylation and Aldehyde Trapping

Abstract

A cascade reaction, consisting of a palladium-catalyzed regioselective aerobic oxidative carbocyclization-borylation of bisallenes and a final aldehyde trapping, afforded triene alcohols with high diastereoselectivity. The cascade reaction occurs under mild reaction conditions and proceeds via an allylboron intermediate that is trapped by the aldehyde in a stereoselective manner.