Concepedia

Publication | Open Access

Aldose reductase mediates endothelial cell dysfunction induced by high uric acid concentrations

DOIFull Paper Access

62

Citations

50

References

2017

Year

Zhiyong Huang, Quan Hong, Xueguang Zhang, Wenzhen Xiao, Liyuan Wang, Shaoyuan Cui, Zhe Feng, Yang Lv, Guangyan Cai, Xiangmei Chen,
Cell Communication and Signaling

Abstract

Our findings indicate that inhibiting AR or degrading H<sub>2</sub>O<sub>2</sub> could protect endothelial function and maintain the antioxidant activities of UA. These findings provide new insight into the role of UA in chronic kidney disease.

References

YearCitations

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