A novel bispecific <scp>DARP</scp>in targeting Fcγ<scp>RIIB</scp> and Fcε<scp>RI</scp>‐bound IgE inhibits allergic responses

Abstract

The described bispecific DARPin protein has the ability to co-ligate FcγRIIB with FcεRI-bound IgE on allergic effector cells and represents an efficient dual-modality to interfere with allergic hypersensitivity reactions.