Multimodal Analgesic Therapy With Gabapentin and Its Association With Postoperative Respiratory Depression

Abstract

The use of gabapentin is associated with increased rates of respiratory depression among patients undergoing laparoscopic surgery. When gabapentinoids are included in multimodal analgesic regimens, intraoperative opioids must be reduced, and increased vigilance for respiratory depression may be warranted, especially in elderly patients.