Publication | Open Access

Argininosuccinate Synthetase 1 Loss in Invasive Bladder Cancer Regulates Survival through General Control Nonderepressible 2 Kinase–Mediated Eukaryotic Initiation Factor 2α Activity and Is Targetable by Pegylated Arginine Deiminase

Tumor BiologyTranscriptional RegulationMedicineArgininosuccinate Synthetase 1Pegylated Arginine DeiminaseMolecular BiologyInvasive Bladder CancerTumor SuppressorCancer GeneticsCancer BiologyCell BiologyCell SignalingMolecular OncologyProtein Biosynthesis