Bioorganic & Medicinal Chemistry · 2016 · 41 citations · 18 references
Natural SciencesChemical EngineeringChemistryBiocatalysisCatalysisReaction EngineeringCatalytic Reaction EngineeringCross-coupling ReactionsHigh-throughput SynthesisPhotocatalysisPhotochemistryReaction Process DesignContinuous-flow Photochemical SynthesisEarly Drug DiscoveryFlow PhotochemistryFlow-based High-throughput SynthesisNickel CatalysisPhotochemical ReactionsPhotoredox CatalysisPhotoredox Cross-coupling
) cross coupling form batch to flow. This new procedure clearly improves the scalability of the previous batch reaction by the reactor's size and operating time reduction, and allows the preparation of interesting compounds for drug discovery in multigram amounts.
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Zhiwei Zuo, Derek T. Ahneman, Lingling Chu et al. · Science · 2014 · 1.6K citations · Full text
Ten key issues in modern flow chemistry
Jens Wegner, Sascha Ceylan, Andreas Kirschning · Chemical Communications · 2011 · 638 citations · Full text
Continuous flow reactors: a perspective
Charlotte Wiles, Paul Watts · Green Chemistry · 2011 · 623 citations
Engineering, Chemical Engineering, Manufacturing Engineering +17