Frontiers in Neurology · 2016 · 24 citations · 12 references
Veterinary MedicineInfectious DiseasesMicrobiologyMedical MicrobiologyOutbreak InvestigationVirologyDiagnosticsEncephalitisVector-borne ZoonosesViral DiagnosticsViral InfectionsAntibodiesGuillain-barré Syndrome PathogenesisNeurological Viral InfectionsZika Virus Infection DiagnosisZika Virus Transmission
We present three patients from Suriname who were diagnosed with Guillain-Barré syndrome (GBS) during the Zika virus (ZIKV) outbreak in this country. One patient had a positive ZIKV urine real-time RT-PCR (qRT-PCR) result. The other two patients had a negative ZIKV urine qRT-PCR but a positive virus neutralization test and presence of IgG antibodies against ZIKV in the serum. Considering the evidence of a past ZIKV infection and absence of evidence for recent infections with the most common preceding infections of GBS, it is very likely that these GBS cases were triggered by ZIKV.
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