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The impairment of glucose-stimulated insulin secretion in pancreatic β-cells caused by prolonged glucotoxicity and lipotoxicity is associated with elevated adaptive antioxidant response

Pancreatic β-CellsBiochemistryMedicineDiabetesPhysiologyDiabetes MellitusGlucose-stimulated Insulin SecretionMetabolismPharmacologyInsulin SignalingProlonged GlucotoxicityOxidative Stress