Recent Advance of Transition Metal-Catalyzed Direct C-H Bond Carboxylation with CO₂

Abstract

Carbon dioxide represents the most abundant carbon source in the world.It is obvious that the utilization of CO 2 to generate chemical products will provide a new strategy for clean energy.Meanwhile, as the main product of CO 2 reactions, carboxylic acids and derivatives have wide application.Among various CO 2 involved carboxylation reactions, the direct carboxylation of C-H bond with CO 2 has attracted much attention recently, which lies in its high efficiency for the synthesis of carboxylic acids.This review summarizes the direct carboxylation of different hybrid C-H bonds with CO 2 in recent years, which focus on transition metal catalyzed reactions for the synthesis of carboxylic acids and its derivatives from CO 2 .