Concepedia

Is It Time to Include CT “Reverse Halo Sign” and qPCR Targeting Mucorales in Serum to EORTC-MSG Criteria for the Diagnosis of Pulmonary Mucormycosis in Leukemia Patients?

Denis Caillot, Stéphane Valot, Ingrid Lafon, Louise Basmaciyan, Marie Lorraine Chrétien, Marc Sautour, Laurence Millon, C. Legouge, Alexandre Payssot, Frédéric Dalle

Open Forum Infectious Diseases · 2016 · 37 citations · 11 references

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Abstract

In 23 leukemia patients with proven (n = 17) or possible (n = 6) pulmonary mucormycosis (PM), the presence of reversed halo sign on computed tomography was strongly associated with the positivity of quantitative polymerase chain reaction assays targeting Mucorales in the serum, confirming the value of these two tools for the diagnosis of PM in this setting.

References

11

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Ben de Pauw, Thomas J. Walsh, J. Peter Donnelly et al. · Clinical Infectious Diseases · 2008 · 4.9K citations · Full text

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Zygomycosis in Europe: analysis of 230 cases accrued by the registry of the European Confederation of Medical Mycology (ECMM) Working Group on Zygomycosis between 2005 and 2007

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Invasive Non- <i>Aspergillus</i> Mold Infections in Transplant Recipients, United States, 2001–2006

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Early diagnosis and monitoring of mucormycosis by detection of circulating DNA in serum: retrospective analysis of 44 cases collected through the French Surveillance Network of Invasive Fungal Infections (RESSIF)

Laurence Millon, Raoul Herbrecht, Frédéric Grenouillet et al. · Clinical Microbiology and Infection · 2015 · 254 citations

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Quantitative Polymerase Chain Reaction Detection of Circulating DNA in Serum for Early Diagnosis of Mucormycosis in Immunocompromised Patients

Laurence Millon, Fabrice Larosa, Q. Lepiller et al. · Clinical Infectious Diseases · 2013 · 240 citations · Full text

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