Immunohistochemical expression of intrarenal renin angiotensin system components in response to tempol in rats fed a high salt diet

Abstract

These findings suggest that a high salt diet leads to changes in the homeostasis and balance between opposing components of the renal RAS in hypertension to favour an increase in Ang II. Chronic antioxidant supplementation can modulate the balance between the natriuretic and antinatriuretic components of the renal RAS.