Polymorphisms of <i>ABAT</i> , <i>SCN2A</i> and <i>ALDH5A1</i> May Affect Valproic Acid Responses in the Treatment of Epilepsy in Chinese

Abstract

This study found three SNPs and one interaction among ABAT, SCN2A and ALDH5A1 were significantly associated with VPA response, which indicated that these genes may play important roles in the pharmacological mechanism of VPA.