The transcription factor PPARα is overexpressed and is associated with a favourable prognosis in <scp>IDH</scp>‐wildtype primary glioblastoma

Abstract

PPARα is overexpressed in primary glioblastoma and high PPARA expression functions as an independent prognostic marker in the glioblastoma TCGA dataset. Further studies are required to explore genetic associations with high PPARA expression and to analyse the predictive role of PPARα expression in glioblastoma models in response to PPARα agonists.