Concepedia

The novel exercise-induced hormone irisin protects against neuronal injury via activation of the Akt and ERK1/2 signaling pathways and contributes to the neuroprotection of physical exercise in cerebral ischemia

Dongjie Li, Yonghua Li, Hongbin Yuan, Lefeng Qu, Pei Wang

Metabolism · 2016 · 304 citations · 49 references

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49

Reversible middle cerebral artery occlusion without craniectomy in rats.

Enrique Zea Longa, Philip R. Weinstein, Shaun W. Carlson et al. · Stroke · 1989 · 7.5K citations · Full text

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A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

Pontus Boström, Jun Wu, Mark P. Jedrychowski et al. · Nature · 2012 · 4.7K citations · Full text

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Exercise Induces Hippocampal BDNF through a PGC-1α/FNDC5 Pathway

Christiane D. Wrann, James P. White, John Salogiannnis et al. · Cell Metabolism · 2013 · 1.4K citations · Full text

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Irisin and FGF21 Are Cold-Induced Endocrine Activators of Brown Fat Function in Humans

Paul Lee, Joyce D. Linderman, Robert J. Brychta et al. · Cell Metabolism · 2014 · 806 citations · Full text

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Irisin Stimulates Browning of White Adipocytes Through Mitogen-Activated Protein Kinase p38 MAP Kinase and ERK MAP Kinase Signaling

Yuan Zhang, Rui Li, Yan Meng et al. · Diabetes · 2013 · 729 citations · Full text

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