Breast Care · 2016 · 21 citations · 5 references
MedicineOncologySurgeryEndocrine OncologyNeoplasiaSurgical OncologyEndocrine Surgical OncologyEndocrine TumorsHer2-positive Breast CancerNeuroendocrine Tumor SurgeryNeuroendocrine Tumor TherapyNeuroendocrine TumorsAdjuvant Her2-directed TherapyHer2 AmplificationHer2 ExpressionHer2 Gene AmplificationHuman Epidermal Growth Factor Receptor 2-Targeted TherapyImmunohistochemical DetectionImmunohistochemical StainingLate Relapse
BACKGROUND: Neuroendocrine carcinoma is an uncommon histology for breast cancer. CASE REPORT: Our patient underwent right quadrantectomy for a neuroendocrine carcinoma in 1984 and had a bone relapse 30 years later. After thorough pathological and immunohistochemical analysis the diagnosis was confirmed and HER2 amplification was observed. Here we discuss the management, rationale and results of HER2-targeted therapy in advanced neuroendocrine breast carcinoma.
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Anna Sapino, Luisella Righi, Paola Cassoni et al. · PubMed · 2000 · 132 citations
Medicine, Cancer Biology, Oncology +12
‘Carcinoid’ tumours of the breast: the morphological spectrum of argyrophil carcinomas
J. G. Azzopardi, Pietro Muretto, P. Goddeeris et al. · Histopathology · 1982 · 124 citations