The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog)

TLDR

The NHGRI‑EBI GWAS Catalog has archived data from published genome‑wide association studies since 2008. In 2015, the database was redesigned and relocated to EMBL‑EBI, adding a new graphical user interface, ontology‑supported search, and improved curation interface. These upgrades have increased data release frequency through automated curation, expanded the catalog with structured ancestry and recruitment data for all studies, and enabled scaling to larger arrays, exome, and sequencing studies to meet evolving design and technology needs.

Abstract

The NHGRI-EBI GWAS Catalog has provided data from published genome-wide association studies since 2008. In 2015, the database was redesigned and relocated to EMBL-EBI. The new infrastructure includes a new graphical user interface (www.ebi.ac.uk/gwas/), ontology supported search functionality and an improved curation interface. These developments have improved the data release frequency by increasing automation of curation and providing scaling improvements. The range of available Catalog data has also been extended with structured ancestry and recruitment information added for all studies. The infrastructure improvements also support scaling for larger arrays, exome and sequencing studies, allowing the Catalog to adapt to the needs of evolving study design, genotyping technologies and user needs in the future.