Concepedia

Publication | Open Access

Bile acid: a potential inducer of colon cancer stem cells

DOIFull Paper Access

163

Citations

50

References

2016

Year

Lulu Farhana, Pratima Nangia‐Makker, Evan Arbit, Kathren Shango, Sarah Sarkar, Hamidah Mahmud, Timothy Hadden, Yingjie Yu, Adhip P.N. Majumdar
Stem Cell Research & Therapy

Abstract

Our results suggest that bile acids, specifically DCA and LCA, induce cancer stemness in colonic epithelial cells by modulating M3R and Wnt/β-catenin signaling and thus could be considered promoters of colon cancer.

References

YearCitations

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