Quarantine versus pathogen‐reduced plasma‐coagulation factor content and rotational thromboelastometry coagulation

Abstract

Pathogen reduction reduces procoagulant and anticoagulant coagulation factors as well as variability. A thrombin-generation assay showed no reduced ETP and no supraphysiological thrombin generation. None of the FFP preparations is likely to be effective for treating fibrinogen deficiency.