Elevated levels of p-Mnk1, p-eIF4E and p-p70S6K proteins are associated with tumor recurrence and poor prognosis in astrocytomas

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Mitogen‐activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

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Life Sciences, Biochemistry, Molecular Biology +7

Human eukaryotic translation initiation factor 4G (eIF4G) recruits Mnk1 to phosphorylate eIF4E

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Dissecting eIF4E action in tumorigenesis

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Phosphorylation of the Eukaryotic Translation Initiation Factor eIF4E Contributes to Its Transformation and mRNA Transport Activities

Ivan Topisirović, Melisa Ruiz‐Gutierrez, Katherine L. B. Borden · Cancer Research · 2004 · 265 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17