Concepedia

Publication | Open Access

β-Amyloid in CSF

DOIFull Paper Access

78

Citations

20

References

2016

Year

Ellis S. van Etten, Marcel M. Verbeek, Jeroen van der Grond, Ronald Zielman, Sanneke van Rooden, Erik W. van Zwet, Anna M. van Opstal, Joost Haan, Steven M. Greenberg, Mark A. van Buchem,
Neurology

Abstract

Decreased levels of CSF Aβ<sub>40</sub> and Aβ<sub>42</sub> occur before HCHWA-D mutation carriers develop clinical symptoms, implicating vascular deposition of both Aβ species as early steps in cerebral amyloid angiopathy pathogenesis. CSF Aβ<sub>40</sub> and Aβ<sub>42</sub> may serve as preclinical biomarkers of cerebral amyloid angiopathy pathology.

References

YearCitations

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