Circumferential viscodilation of Schlemm's canal with a flexible microcannula during non-penetrating glaucoma surgery

Abstract

INTRODUCTION MATERIALS AND METHODS RESULTS DISCUSSION Abstract Purpose: A pilot study was performed to evaluate the safety and performance of the flexible Ophthalmic Microcannula (iScience Surgical Corporation, Menlo Park, CA) in accessing and dilating Schlemm's canal during non-penetrating surgery for the treatment of glaucoma. Materials and Methods: Patients with previous surgery, angle recession and combined cases with cataract surgery were allowed for inclusion. Fifty-six glaucomatous eyes with open angles of 56 subjects underwent viscocanalostomy or deep sclerectomy surgery for the treatment of glaucoma by four US surgeons. The flexible microcannula was introduced into Schlemm's canal at the scleral dissection site and the canal was progressively cannulated, up to the entire canal circumference. Patients were assessed at 1 day, 1 week, and 1, 3, and 6 months following the procedure. A prototype high resolution ultrasound imaging system was used to characterize the anterior segment and Schlemm's canal when possible.