Rhodium(III)/Amine Synergistically Catalyzed Enantioselective Alkylation of Aldehydes with <i>α</i>,<i>β</i>‐Unsaturated 2‐Acyl Imidazoles

Abstract

Abstract A synergistic catalysis combination of chiral‐at‐metal rhodium complex and amine catalyst was developed for enantioselective alkylation of aldehydes with α , β ‐unsaturated 2‐acyl imidazoles. The corresponding adducts were obtained in good yields with excellent enantioselectivities (up to 99% ee ).