Studies on <i>v</i>‐triazoles. Part V. Acylation, alkylation and sulphonation reactions of ethyl 5‐(4‐hydroxyphenoxy)‐1<i>H‐v</i>‐triazole‐4‐carboxylate

Abstract

Abstract The alkylation of 5‐(4‐hydroxyphenoxy)‐1 H‐v ‐triazolecarboxylate ( 1 ) under alkaline conditions was shown to yield exclusively isomeric N‐2 and N‐3 alkylation products, the structures of which were assigned by ir, 1 H nmr and, 3 C nmr spectroscopy. Acylation and sulphonation under similar conditions resulted in exclusive attack at the phenolic oxygen of 1 , possibly by the migration of an initially formed N ‐derivative.