Concepedia

Synthesis of Novel Triazole‐incorporated Isatin Derivatives as Antifungal, Antitubercular, and Antioxidant Agents and Molecular Docking Study

Mubarak H. Shaikh, Dnyaneshwar D. Subhedar, Firoz A. Kalam Khan, Jaiprakash N. Sangshetti, Laxman Nawale, Manisha Arkile, Dhiman Sarkar, Bapurao B. Shingate

Journal of Heterocyclic Chemistry · 2016 · 56 citations · 25 references

DOI

Concepts

Abstract

A library of 1,2,3‐triazoles efficiently prepared via click chemistry and evaluated for their antifungal, antitubercular, antioxidant, cytotoxicity, molecular docking and ADME prediction.

References

25

A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective “Ligation” of Azides and Terminal Alkynes

Vsevolod V. Rostovtsev, Luke G. Green, Valery V. Fokin et al. · Angewandte Chemie International Edition · 2002 · 11.5K citations

, , +8

Peptidotriazoles on Solid Phase:  [1,2,3]-Triazoles by Regiospecific Copper(I)-Catalyzed 1,3-Dipolar Cycloadditions of Terminal Alkynes to Azides

Christian W. Tornøe, Caspar Christensen, Morten Meldal · The Journal of Organic Chemistry · 2002 · 8.5K citations

, , +12

Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay.

Michael C. Alley, Dominic A. Scudiero, Anne Monks et al. · PubMed · 1988 · 3.1K citations

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Fast Calculation of Molecular Polar Surface Area as a Sum of Fragment-Based Contributions and Its Application to the Prediction of Drug Transport Properties

Peter Ertl, Bernhard Rohde, Paul M. Selzer · Journal of Medicinal Chemistry · 2000 · 3K citations

, , +15

Antioxidant activity of Nigella sativa essential oil

M. Burits, Franz Bučar · Phytotherapy Research · 2000 · 1.9K citations

, , +17