Concepedia

Mitigation of Pre-existing Antibodies to a Biotherapeutic in Non-clinical Species When Establishing Anti-drug Antibody Assay Cutpoint

Seema C Kumar, Jason A DelCarpini, Qiang Qu, Martin Kane, Boris Gorovits

The AAPS Journal · 2016 · 11 citations · 8 references

DOI

Concepts

References

8

Model Selection and Model Averaging in Phylogenetics: Advantages of Akaike Information Criterion and Bayesian Approaches Over Likelihood Ratio Tests

David Posada, Thomas R. Buckley · Systematic Biology · 2004 · 4K citations · Full text

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Statistical methods and tool for cut point analysis in immunogenicity assays

Lanju Zhang, Jianchun Jason Zhang, Harry Yang · Journal of Immunological Methods · 2013 · 44 citations

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Statistical considerations for calculation of immunogenicity screening assay cut points

David Hoffman, Marion Berger · Journal of Immunological Methods · 2011 · 40 citations

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Pre-Existing Biotherapeutic-Reactive Antibodies: Survey Results Within the American Association of Pharmaceutical Scientists

Xue Li, Michele Fiscella, Manoj Rajadhyaksha et al. · The AAPS Journal · 2013 · 39 citations

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Statistical approaches for the determination of cut points in anti-drug antibody bioassays

Frank Schaarschmidt, Matthias Hofmann, Thomas Jaki et al. · Journal of Immunological Methods · 2015 · 27 citations

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