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A novel 4,6-disubstituted-1,2,4-triazolo-1,3,4-thiadiazole derivative inhibits tumor cell invasion and potentiates the apoptotic effect of TNFα by abrogating NF-κB activation cascade

Medicinal ChemistryNf-κb Activation CascadeMedicineImmunologyApoptotic EffectPharmacological AgentPharmacotherapyAnti-cancer AgentDrug DevelopmentPharmacologyPharmaceutical ChemistryTumor BiologyDrug Discovery