Induced pluripotent stem cells from human hair follicle keratinocytes as a potential source for <i>in vitro</i> hair follicle cloning

Abstract

Hair follicles represent a valuable keratinocytes source for <i>in vitro</i> hair cloning for use in treating hair balding or grafting in burn patients. Our significant findings in this report proved that hair follicles could be used to produce pluripotent stem cells and suggested that the genetic and micro-environmental elements of hair follicles might trigger higher and more efficient hair follicles re-differentiation.