Nanoparticle delivery of chemotherapy combination regimen improves the therapeutic efficacy in mouse models of lung cancer

Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA–PEG nanoparticles

Shanta Dhar, Frank Gu, Róbert Langer et al. · Proceedings of the National Academy of Sciences · 2008 · 982 citations · Full text

Ethylene Glycol, Nanotherapeutics, Engineering +16

Synergistic drug combinations tend to improve therapeutically relevant selectivity

Joseph Lehár, Andrew Krueger, William Avery et al. · Nature Biotechnology · 2009 · 940 citations · Full text

Drug Repositioning, Synergistic Drug Combinations, Pharmacology +4

Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy

Nagesh Kolishetti, Shanta Dhar, Pedro M. Valencia et al. · Proceedings of the National Academy of Sciences · 2010 · 563 citations

Nanoparticles, Ethylene Glycol, Nanotherapeutics +24

Pt(IV) Prodrugs Designed to Bind Non-Covalently to Human Serum Albumin for Drug Delivery

Yao‐Rong Zheng, Kogularamanan Suntharalingam, Timothy C. Johnstone et al. · Journal of the American Chemical Society · 2014 · 425 citations · Full text

Pharmaceutical Science, Chemical Biology, Axial Ligands +17

A Convergent Synthetic Platform for Single-Nanoparticle Combination Cancer Therapy: Ratiometric Loading and Controlled Release of Cisplatin, Doxorubicin, and Camptothecin

Longyan Liao, Jenny Liu, Erik C. Dreaden et al. · Journal of the American Chemical Society · 2014 · 364 citations · Full text

Nanoparticles, Engineering, Convergent Synthetic Platform +21