Therapeutic potential of ADAM17 modulation in gastric cancer through regulation of the EGFR and TNF-α signalling pathways

Global cancer statistics

Ahmedin Jemal, Freddie Bray, Jacques Ferlay et al. · CA A Cancer Journal for Clinicians · 2011 · 55K citations · Full text

Medicine, Oncology, Cancer Epidemiology +15

Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α

Marcia L. Moss, S.-L. Catherine Jin, Marcos E. Milla et al. · Nature · 1997 · 1.6K citations

Life Sciences, Biochemistry, Molecular Biology +11

Selective Roles for Tumor Necrosis Factor α-converting Enzyme/ADAM17 in the Shedding of the Epidermal Growth Factor Receptor Ligand Family

C. Leann Hinkle, Susan W. Sunnarborg, David R. Loiselle et al. · Journal of Biological Chemistry · 2004 · 156 citations · Full text

Life Sciences, Biochemistry, Cell Biology +9

ADAM-17 Expression in Breast Cancer Correlates with Variables of Tumor Progression

Patricia M. McGowan, Bríd M. Ryan, Arnold D. Hill et al. · Clinical Cancer Research · 2007 · 116 citations

Medicine, Molecular Biology, Oncology +14

Chemoprevention of dietary digitoflavone on colitis-associated colon tumorigenesis through inducing Nrf2 signaling pathway and inhibition of inflammation

Yang Yang, Xueting Cai, Jie Yang et al. · Molecular Cancer · 2014 · 94 citations · Full text

Medicine, Oncology, Pharmacology +17