Concepedia

Tanshinone IIA Affects Autophagy and Apoptosis of Glioma Cells by Inhibiting Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin Signaling Pathway

Lijuan Ding, Lijuan Ding, Shudong Wang, Shudong Wang, Wei‐Yao Wang, Wei‐Yao Wang, Peng Lv, Peng Lv, Donghai Zhao, Donghai Zhao,

Pharmacology · 2016 · 47 citations · 29 references

DOI

Abstract

Tan IIA could suppress the viability of U251 cells and induce cell apoptosis and autophagy, which might be related to the inhibition of the PI3K/Akt/mTOR signal pathway.

References

29

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Yukihiro Kabeya · The EMBO Journal · 2000 · 6.5K citations · Full text

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Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells

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Autophagy Is Required for Glucose Homeostasis and Lung Tumor Maintenance

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The Prognostic Significance of Phosphatidylinositol 3-Kinase Pathway Activation in Human Gliomas

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Roles of the Akt/mTOR/p70S6K and ERK1/2 Signaling Pathways in Curcumin-Induced Autophagy

Naoki Shinojima, Tomohisa Yokoyama, Yasuko Kondo et al. · Autophagy · 2007 · 336 citations · Full text

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