High hyperdiploid acute lymphoblastic leukemia (ALL)—A 25‐year population‐based survey of the Austrian ALL‐BFM (Berlin‐Frankfurt‐Münster) Study Group

Abstract

In line with previous studies, our retrospective analysis shows that MCN and specific trisomies are relevant prognostic indicators in an ALL-BFM cohort of patients with HD ALL. However, considering the current dominant role of minimal residual disease monitoring for prognostic stratification in ALL, including this particular subgroup, it is unlikely that this information is compelling enough to be utilized for refined risk classification in future ALL-BFM treatment protocols.