Publication | Closed Access
Synthesis of 2-arylated thiadiazolopyrimidones by Suzuki–Miyaura cross-coupling: a new class of nucleotide pyrophosphatase (NPPs) inhibitors
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Citations
39
References
2016
Year
Cell DeathPathologySuzuki–miyaura Cross-couplingNucleotide PyrophosphataseCancer MetastasisOxidative StressOsteoarthritisRedox SignalingBiochemistryType 2Drug DevelopmentPharmacologyCell BiologyProtein PhosphorylationSignal TransductionNew ClassMedicineSynthetic ChemistryDrug Discovery
Over expression of nucleotide pyrophosphatase (NPPs) activity is associated with chondrocalcinosis, osteoarthritis, type 2 diabetes, neurodegenerative diseases, allergies and cancer metastasis.
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