Magnetically separable graphene oxide anchored sulfonic acid: a novel, highly efficient and recyclable catalyst for one-pot synthesis of 3,6-di(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridine-5-carbonitriles in deep eutectic solvent under microwave irradiation

Abstract

A magnetic separable sulfonic acid catalyst was prepared and applied for the synthesis of 3,6-di(pyridin-3-yl)-1<italic>H</italic>-pyrazolo[3,4-<italic>b</italic>]pyridine-5-carbonitriles via three-component reaction of 1-phenyl-3-(pyridin-3-yl)-1<italic>H</italic>-pyrazol-5-amine, β-ketonitrile and aldehydes in DES.