Dexamethasone Alters the Appetite Regulation via Induction of Hypothalamic Insulin Resistance in Rat Brain

Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease – is this type 3 diabetes?

Eric van Steen, Benjamin M. Terry, Enrique J. Rivera et al. · Journal of Alzheimer s Disease · 2005 · 1.7K citations

Life Sciences, Neurobiology, Neuroscience +17

Consumption of a Fat-Rich Diet Activates a Proinflammatory Response and Induces Insulin Resistance in the Hypothalamus

Cláudio Teodoro de Souza, Eliana P. Araújo, Silvana Bordin et al. · Endocrinology · 2005 · 1.2K citations · Full text

Life Sciences, Endocrinology, Physiology +17

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

Alfred H. Schinkel, Els Wagenaar, Liesbeth van Deemter et al. · Journal of Clinical Investigation · 1995 · 1.1K citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity

Karim El-Haschimi, Dominique D. Pierroz, Stanley M. Hileman et al. · Journal of Clinical Investigation · 2000 · 882 citations · Full text

Life Sciences, Endocrinology, Physiology +14

Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance

Qingchun Tong, Chian-Ping Ye, Juli E. Jones et al. · Nature Neuroscience · 2008 · 689 citations

Life Sciences, Neurobiology, Neuroscience +15