<i>BMPR2</i> Mutations Influence Phenotype More Obviously in Male Patients With Pulmonary Arterial Hypertension

Abstract

BMPR2 mutations influence phenotype more obviously in male PAH patients. The pathogenesis of female PAH patients is more complicated, and the influence of BMPR2 mutations may be modified by other unknown factors, making disparities in the prognosis between female mutation carriers and noncarriers less evident.