An Exploratory Randomized Control Study of Combination Cytokine and Adult Autologous Bone Marrow Progenitor Cell Administration in Patients with Ischaemic Cardiomyopathy: The REGENERATE-IHD Clinical Trial

Abstract

We have shown that G-CSF combined with autologous i.m. BMCs has a beneficial effect on cardiac function and symptoms. However, this result should be considered preliminary in support of a clinical benefit of i.m. stem cell infusion in 'no option' patients and needs further exploration in a larger study.