Thrombogenicity of flow diverters in an ex vivo shunt model: effect of phosphorylcholine surface modification

Abstract

In this preclinical model, we have shown that the Shield Technology phosphorylcholine modification reduces the platelet-specific thrombogenicity of a flow diverter under physiologically relevant flow with and without DAPT. We have further identified increased fibrin-driven thrombogenicity associated with FRED relative to PED.