Phagocyte-specific S100A8/A9 is upregulated in primary Sjögren's syndrome and triggers the secretion of pro-inflammatory cytokines in vitro. - Concepedia

Concepedia

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Phagocyte-specific S100A8/A9 is upregulated in primary Sjögren's syndrome and triggers the secretion of pro-inflammatory cytokines in vitro.

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References

2017

Year

Charles Nicaise, Laura Weichselbaum, Liliane Schandené, Valérie Gangji, Florence Dehavay, J Bouchat, Benoît Balau, Thomas Vogl, Muhammad Shahnawaz Soyfoo

Abstract

S100A8/A9 is increased in pSS patients contributing to the in vitro increased production of pro-inflammatory cytokines. As such, S100A8/A9 in concert with other cytokines might contribute to the pathogenesis of pSS.