Synthesis and biological evaluation of memantine nitrates as a potential treatment for neurodegenerative diseases

Zheng Liu, Yang Si, Xiaoyong Jin, Gaoxiao Zhang, Baojian Guo, Haiyun Chen, Pei Yu, Yewei Sun, Zaijun Zhang, Yuqiang Wang

MedChemComm · 2016 · 33 citations · 18 references

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Abstract

A series of memantine nitrate derivatives, as dual functional compounds with neuroprotective and vasodilatory activity for neurodegenerative diseases, was designed and synthesized.

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